While not continuous like UF and Miami, the series with Louisville is one of the oldest in Florida State’s history. Louisville and FSU first matched up in 1952, the inaugural season in which the Seminoles played the majority of their games against what would today be considered “FBS” programs. In fact, FSU only played two programs prior to 1952 that are currently playing FBS football: Troy State (now known as Troy University) every year from 1947-1951 and the University of Miami in 1951.
For whatever reason, the FSU/UL series is one marked mostly by blowouts on both sides. 13 of the 18 games have been decided by 20 points or more, with a 14th coming as a 17-0 shutout victory for FSU. FSU shut out Louisville for three consecutive years during the 1979, 1980, and 1981 seasons. The combined score of those three games was 96-0.
The opening betting line on the game is the Seminoles favored by five points. Florida State is coming off a win against Northern Illinois in which it covered a spread of ten points. Louisville is coming off a loss against Virginia in which it failed to cover a spread of four points. Florida State’s record against the spread this season is 1-2. The game is set to kick of Saturday (9/29/18) at 3:30pm.